Author

P. D. Moerland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Organism:human· 5 Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Approach:deep learning· 1

Frequent Co-Authors

A. Jongejan· 4 shared A. E. Neele· 2 shared F. J. Bemelman· 2 shared J. W. van der Heijden· 2 shared L. Vogt· 2 shared M. L. Hilhorst· 2 shared Y. Vegting· 2 shared A. Aartse· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersImmunology

A. Jongejan

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Infiltrative classical monocyte-derived and SPP1 lipid-associated macrophages mediate inflammation and fibrosis in ANCA-associated glomerulonephritis

Y. Vegting, A. Jongejan, A. E. Neele, N. Claessen, G. Sela, K. H. Prange, J. Kers, J. J. Roelofs, J. W. van der Heijden, O. J. de Boer, E. B. Remmerswaal, L. Vogt, F. J. Bemelman, M. P. de Winther, P. D. Moerland, M. L. Hilhorst

This paper identifies specific macrophage subsets in ANCA-associated glomerulonephritis that drive inflammation and fibrosis, suggesting therapeutic targets.

bioRxiv · Mar 13, 2024 · PreprintImmunology

Cardiovascular risk in ANCA-associated vasculitis: monocyte phenotyping reveals distinctive signatures between serological subsets

Y. Vegting, K. M. Hanford, A. Jongejan, G. R. Gajadin, M. Versloot, N. D. van der Bom-Baylon, T. Dekker, E. L. Penne, J. W. van der Heijden, E. Houben, F. J. Bemelman, A. E. Neele, P. D. Moerland, L. Vogt, J. Kroon, M. L. Hilhorst

This study identifies distinct monocyte phenotypes and gene expression patterns in ANCA-associated vasculitis serotypes, linking them to cardiovascular risk.

bioRxiv · Jan 16, 2024Immunology

Identification and mapping of human lymph node stromal cell subsets by combining single-cell RNA sequencing with spatial transcriptomics.

C. Grasso, J. Roet, C. Gago de Graca, J. F. Semmelink, E. Remmerswaal, A. Jongejan, P. D. Moerland, R. E. Mebius, L. G. M. van Baarsen

The paper identifies and maps human lymph node stromal cell subsets using scRNA-seq and spatial transcriptomics, revealing their spatial distribution and potential interactions with lymphocytes.

bioRxiv · Aug 18, 2023Cell Biology

A public antibody class recognizes a novel S2 epitope exposed on open conformations of SARS-CoV-2 spike

M. Claireaux, T. G. Caniels, M. de Gast, J. Han, D. Guerra, G. Kerster, B. D. van Schaik, A. Jongejan, A. I. Schriek, M. Grobben, P. J. Brouwer, K. van der Straten, Y. Aldon, J. Capella-Pujol, J. L. Snitselaar, , M. J. van Gils

The paper identifies a novel S2 epitope recognized by a public antibody class in SARS-CoV-2-reactive B cells, which becomes exposed on vaccine-optimized spike proteins.

bioRxiv · Dec 1, 2021Immunology

Time-resolved profiling reveals ATF3 as a novel mediator of endocrine resistance in breast cancer

S. Borgoni, E. Sofyali, M. Soleimani Dodaran, H. Wilhelm, K. Mueller-Decker, R. Will, A. Noronha, P. J. Verschure, Y. Yarden, L. Magnani, A. H. C. van Kampen, P. D. Moerland, S. Wiemann

This study identifies ATF3 as a novel mediator of endocrine resistance in breast cancer through time-resolved profiling and validates its role in key signaling pathways and clinical relevance.

bioRxiv · Jun 8, 2020Cancer Biology