Author

L. Whitesell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. Detappe· 1 shared A. Tsherniak· 1 shared G. Kugener· 1 shared H. R. Keys· 1 shared I. M. Ghobrial· 1 shared J. Di Trani· 1 shared J. L. Markley· 1 shared J. L. Rubinstein· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Detappe

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III

J. Di Trani, Z. Liu, L. Whitesell, P. Brzezinski, L. Cowen, J. L. Rubinstein

This study uses cryoEM to analyze the structure and dynamics of the Rieske head domain in Candida albicans Complex III and shows how Inz-5 alters its conformational equilibrium.

bioRxiv · May 18, 2021Biochemistry

Inhibition of mitochondrial ferredoxin 1 (FDX1) prevents adaptation to proteotoxic stress

P. Tsvetkov, A. Detappe, K. Cai, H. R. Keys, Z. Brune, W. Ying, P. Thiru, M. Reidy, G. Kugener, A. Tsherniak, S. Santagata, L. Whitesell, J. L. Markley, I. M. Ghobrial, S. Lindquist

This study identifies FDX1 inhibition as a strategy to prevent proteasome inhibitor resistance in cancer by targeting mitochondrial Fe-S cluster biosynthesis.

bioRxiv · Mar 24, 2018Cancer Biology