L. Zhuang

Unraveling the Complexity of Abdominal Aortic Aneurysm: Multiplexed Imaging Insights into C-Reactive Protein-Related Variations

This study uses multiplexed imaging to analyze immune and stromal cell changes in abdominal aortic aneurysms (AAAs) based on C-reactive protein (CRP) levels, revealing distinct immune cell distributions and macrophage phenotypes associated with CRP deposition.

Multi-omics map revealed PPARalpha activation protecting against myocardial ischemia-reperfusion injury by maintaining cardiac metabolic homeostasis

The paper identifies PPARalpha activation as protective against myocardial ischemia-reperfusion injury by maintaining cardiac metabolic homeostasis, using multi-omics data from rat hearts.

Cardiac patch treatment alleviates ischemic cardiomyopathy correlated with reverting Piezo1/2 expression by unloading left ventricular myocardium

This study shows cardiac patches reduce ischemic cardiomyopathy by lowering mechanical load and reverting Piezo1/2 expression in the left ventricle.

The nonstructural protein 5 of coronaviruses antagonizes GSDMD-mediated pyroptosis by cleaving and inactivating its pore-forming p30 fragment

This study identifies how coronavirus Nsp5 protein inhibits pyroptosis by cleaving GSDMD, preventing pore formation and viral replication inhibition.

Recombinant HcGAPDH Protein Expressed on Probiotic Bacillus subtilis Spores Protects Sheep from Haemonchus contortus Infection by Inducing both Humoral and Cell-mediated Responses

This paper shows that recombinant Bacillus subtilis spores expressing H. contortus GAPDH protect sheep from infection by boosting immune responses and reducing parasite burden.

The electrically conductive pili of Geobacter soli

This paper investigates the role of electrically conductive pili in Geobacter soli by deleting the pilA gene and shows that these pili are required for extracellular electron transfer, while heterologous expression in G. sulfurreducens reduces c-type cytochrome content and EET capacity.