Osteosarcoma-enriched transcripts paradoxically generate osteosarcoma-suppressing extracellular proteins
K. Li, Q. Huo, N. H. Dimmitt, G. Qu, J. Bao, P. H. Pandya, M. R. Saadatzadeh, K. Bijangi-Vishehsaraei, M. A. Kacena, K. E. Pollok, C.-C. Lin, B.-Y. Li, H. Yokota
The paper identifies osteosarcoma-enriched transcripts that encode extracellular tumor-suppressing proteins, suggesting a paradoxical therapeutic strategy using OS transcriptomes.
eLife · Mar 21, 2023Peer-reviewedCancer Biology