Author

Lakeshia Bush

Cleveland Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Assay:ATAC-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:spatial transcriptomics· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Andrew S. BombackiD· 3 shared Blue B. LakeiD· 3 shared Daria BarwinskaiD· 3 shared Jeffrey B. HodginiD· 3 shared John R. SedoriD· 3 shared Katherine J. KellyiD· 3 shared Michael J. FerkowicziD· 3 shared Olivia Balderes· 3 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

Andrew S. BombackORCID

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Author profile →

3 papers

Recent·Most cited

A MEF2C transcription factor network regulates proliferation of glomerular endothelial cells in diabetic kidney disease

Ricardo Melo Ferreira, Debora L. Gisch, Carrie L. Phillips, Ying‐Hua Cheng, Nicholas Lucarelli, Soumya Yennapureddy, Maansi Asthana, Blue B. Lake, William S. Bowen, Fang Fang, Mahla Asghari, Angela R. Sabo, Daria Barwinska, Michael J. Ferkowicz, Robert D. Toto, , Tashas Cameron-Wheeler

This study identifies a MEF2C transcription factor network that regulates endothelial cell proliferation in diabetic kidney disease and shows that SGLT2i treatment can reverse its dysregulation.

Kidney International · Apr 27, 2026Peer-reviewedCell Biology

The chromatin landscape of healthy and injured cell types in the human kidney

Debora L. Gisch, Michelle Brennan, Blue B. Lake, Jeannine M. Basta, Mark S. Keller, Ricardo Melo Ferreira, Shreeram Akilesh, Reetika R. Ghag, Charles Lu, Ying‐Hua Cheng, Kimberly S. Collins, Samir V. Parikh, Brad H. Rovin, Lynn Robbins, Lisa Stout, , Joana P. Gonçalves

The paper defines the chromatin landscape of healthy and injured kidney cells using multi-omics data, identifying regulatory elements and transcription factor networks involved in injury response.

Nature Communications · Jan 10, 2024Peer-reviewedMolecular Biology

An atlas of healthy and injured cell states and niches in the human kidney

Blue B. Lake, Rajasree Menon, Seth Winfree, Qiwen Hu, Ricardo Melo Ferreira, Kian Kalhor, Daria Barwinska, Edgar A. Otto, Michael J. Ferkowicz, Dinh H. Diep, Nongluk Plongthongkum, Amanda L. Knoten, Sarah M. Urata, Laura H. Mariani, Abhijit S. Naik, , Ljiljana Paša‐Tolić

The paper creates a high-resolution cellular atlas of healthy and injured kidney cell states and niches using single-cell and spatial technologies, identifying molecular signatures and pathways related to kidney injury.

Nature · Jul 19, 2023Peer-reviewedGenomics