Author

Laura Jentschel

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alexandre DavidiD· 1 shared Anne BlangyiD· 1 shared Anne VincentiD· 1 shared Armelle ChoquetiD· 1 shared Arnaud M. VigneroniD· 1 shared Céline Bouclier· 1 shared Celine MANDIERiD· 1 shared Christelle MachoniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Alexandre DavidORCID

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2 papers

Recent·Most cited

ARHGAP10 is a novel microtubule-associated protein that regulates the resorption activity of osteoclasts

Laura Jentschel, Anne Blangy, Guillaume Bompard

This study identifies ARHGAP10 as a microtubule-associated protein critical for osteoclast function, showing it regulates actin ring dynamics and resorption activity through its interaction with microtubules and RHO-GTPases.

Journal of Biological Chemistry · Aug 30, 2025Peer-reviewedCell Biology

Translational control of cell plasticity drives 5-FU tolerance

Mounira Chalabi‐Dchar, Olivia Villeronce, Julie Ripoll, Anne Vincent, Tanguy Fenouil, Rita Khoueiry, Jérôme Kucharczak, Laura Jentschel, Frédéric Catez, Arnaud M. Vigneron, Julie Tréguier, Celine MANDIER, Céline Bouclier, Jihane Boubaker-Vitre, Louise LAGERQVIST, , Jean‐Jacques Diaz

The paper shows 5-FU induces translational reprogramming in colorectal cancer cells, enhancing drug tolerance through pro-tumoral gene expression and IL-8 overexpression.

bioRxiv · Jul 3, 2024 · PreprintCancer Biology