Author

Mounira Chalabi‐Dchar

Lyon 1 UniversitéORCID 0000-0002-4539-589XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

Frédéric CateziD· 2 shared Jean‐Jacques DiaziD· 2 shared Tanguy FenouiliD· 2 shared Alexandre DavidiD· 1 shared Angéline Gaucherot· 1 shared Anne VincentiD· 1 shared Armelle ChoquetiD· 1 shared Arnaud M. VigneroniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Frédéric CatezORCID

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2 papers

Recent·Most cited

Cancer BiologyBreast Cancer ResearchPeer-reviewedNov 13, 2025

Fibrillarin-mediated ribosomal RNA maturation is a novel therapeutic vulnerability in triple-negative breast cancer

Camille Jouines, Piero Lo Monaco, Angéline Gaucherot…·Frédéric Catez

This study identifies ribosome biogenesis as a therapeutic vulnerability in TNBC, showing that inhibiting rRNA maturation via Fibrillarin or RNA Pol I reduces tumor growth without significant cell death.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJul 3, 2024

Translational control of cell plasticity drives 5-FU tolerance

Mounira Chalabi‐Dchar, Olivia Villeronce, Julie Ripoll…·Jean‐Jacques Diaz

The paper shows 5-FU induces translational reprogramming in colorectal cancer cells, enhancing drug tolerance through pro-tumoral gene expression and IL-8 overexpression.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky