Rita Khoueiry

This study shows that disrupting BAP1, an epigenetic regulator, causes chromatin remodeling and leads to breast cancer stem cell-like properties and altered glycosylation.

The paper shows 5-FU induces translational reprogramming in colorectal cancer cells, enhancing drug tolerance through pro-tumoral gene expression and IL-8 overexpression.

This study identifies TET1 as a key mediator of gene-environment interactions in congenital malformations, showing how maternal folate status and genetic background influence DNA methylation and NTD susceptibility.

This study identifies sequential activation of Tet1 and Oct4 during iPSC reprogramming, revealing distinct DNA demethylation waves and epigenetic dynamics critical for generating high-quality iPSCs.