Author

Laurence du Merle

Institut Pasteur

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Shaynoor DramsiiD· 3 shared Wooi Keong TehiD· 2 shared Adriana Mihalache· 1 shared Alexandra Doloy· 1 shared Alexandre ChenaliD· 1 shared Antonina GonetiD· 1 shared Ariel MéchalyiD· 1 shared Armel BezaultiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersMicrobiology

Shaynoor DramsiORCID

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Author profile →

3 papers

Recent·Most cited

A Seven-Protein Assembly Promotes Stability, Neutralisation and Secretion of the T7SSb LXG-effector TelE

Palak Agrawal, Antonina Gonet, Doreen Toko, Johanna Gorkisch, Dorothée Raoux‐Barbot, Laurence du Merle, Eléonore Bouscasse, Mariette Matondo, Ariel Méchaly, Wooi Keong Teh, Armel Bezault, Alexandre Chenal, Marco Bellinzoni, Shaynoor Dramsi, Francesca Gubellini

The paper identifies a seven-protein complex that stabilizes and facilitates the secretion of the T7SSb effector TelE in SGG.

bioRxiv · Mar 13, 2026 · PreprintMicrobiology

Colorectal Cancer-Associated Streptococcus gallolyticus: A Hidden Diversity Exposed

Bruno Périchon, Thomas Cokelaer, Wooi Keong Teh, Laurence du Merle, Laurence Ma, Marie Touchon, Alexandra Doloy, Claire Poyart, Michael Givskov, Patrick Trieu‐Cuot, Shaynoor Dramsi

This study sequences and analyzes genetic diversity in SGG isolates associated with colorectal cancer, revealing no specific pathogenicity island and highlighting surface proteins and other factors involved in host colonization.

Journal of Bacteriology · Aug 14, 2025Peer-reviewedMicrobiology

Induction of intercrypt goblet cells upon bacterial infection

Renaud Léonard, Ewa Pasquereau-Kotula, Edwige Madec, Benjamin Marsac, Adriana Mihalache, Laurence du Merle, Jordan Denis, Corentin Spriet, Philippe Jean Sansonetti, Shaynoor Dramsi, Catherine Robbe Masselot

This study shows that bacterial infection induces intercrypt goblet cells (icGCs) in mice, which produce a protective mucus layer with unique glycosylation that blocks pathogens.

Gut Microbes · Nov 14, 2024Peer-reviewedBiochemistry