Author

Francesca Gubellini

Centre National de la Recherche ScientifiqueORCID 0000-0002-2155-9765Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Ariel MéchalyiD· 2 shared Adrià SoguesiD· 1 shared Alexandra AubryiD· 1 shared Alexandre ChenaliD· 1 shared Anne Marie WehenkeliD· 1 shared Antoine GedeoniD· 1 shared Antonina GonetiD· 1 shared Armel BezaultiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

Ariel MéchalyORCID

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3 papers

Recent·Most cited

Assessing Corynebacterium glutamicum as a surrogate of Mycobacterium tuberculosis for DNA gyrase inhibitor design.

Yaëlle Wormser, Emilie Yab, Adrià Sogues, Francesca Gubellini, Estelle Capton, Estelle Lecat, Mathilde Ben Assaya, Alexandra Aubry, Ariel Méchaly, Pedro M. Alzari, Anne Marie Wehenkel, Antoine Gedeon, S. Petrella

This paper validates Corynebacterium glutamicum as a non-pathogenic surrogate for Mycobacterium tuberculosis to study DNA gyrase and discover new inhibitors.

bioRxiv · Jun 25, 2026 · PreprintMicrobiology

A Seven-Protein Assembly Promotes Stability, Neutralisation and Secretion of the T7SSb LXG-effector TelE

Palak Agrawal, Antonina Gonet, Doreen Toko, Johanna Gorkisch, Dorothée Raoux‐Barbot, Laurence du Merle, Eléonore Bouscasse, Mariette Matondo, Ariel Méchaly, Wooi Keong Teh, Armel Bezault, Alexandre Chenal, Marco Bellinzoni, Shaynoor Dramsi, Francesca Gubellini

The paper identifies a seven-protein complex that stabilizes and facilitates the secretion of the T7SSb effector TelE in SGG.

bioRxiv · Mar 13, 2026 · PreprintMicrobiology

A ubiquitin-like protein controls assembly of a bacterial Type VIIb secretion system

Gabriel Umaji Oka, Nathanaël Benoit, Axel Siroy, Francesca Gubellini, Esther Marza, Rémi Fronzes

This study presents the cryo-EM structure of a bacterial Type VIIb secretion system core complex, showing how a ubiquitin-like protein coordinates its assembly and function.

Science Advances · Nov 21, 2025Peer-reviewedMicrobiology