The Epithelial Na+ Channel UNC-8 promotes an endocytic mechanism that recycles presynaptic components from old to new boutons in remodeling neurons
Andrea Cuentas-Condori, Siqi Chen, Mia Krout, Kristin L. Gallik, John A. Tipps, Casey D. Gailey, Leah Flautt, Hongkyun Kim, Ben Mulcahy, Mei Zhen, Janet E. Richmond, David M. Miller
The paper shows that UNC-8, an ENaC protein, promotes Ca2+-dependent endocytosis to dismantle and recycle presynaptic components during neuronal remodeling in C. elegans.
Cell Reports · Oct 30, 2023Peer-reviewedNeuroscience