Evolutionarily divergent mTOR remodels the translatome to drive rapid wound closure and regeneration
Olena Zhulyn, Hannah D. Rosenblatt, Leila Shokat, Shizhong A. Dai, Duygu Kuzuoğlu‐Öztürk, Zijian Zhang, Davide Ruggero, Kevan M. Shokat, Maria Barna
This study identifies mTOR-mediated translational activation as a key mechanism for rapid wound closure and regeneration in axolotls, distinct from non-regenerative mammals.
bioRxiv · Oct 28, 2021 · PreprintDevelopmental Biology