Author

Gerald C. Tiu

Stanford MedicineORCID 0000-0002-4090-9863Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:multiome· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Craig H. KerriD· 2 shared Maria BarnaiD· 2 shared Adele XuiD· 1 shared Alicia SolórzanoiD· 1 shared Andrew M. WatkinsiD· 1 shared Bojan Tunguz· 1 shared Christian A. ChoeiD· 1 shared Craig M. ForesteriD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Craig H. KerrORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedMar 22, 2022

Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics

Kathrin Leppek, Gun Woo Byeon, Wipapat Kladwang…·Rhiju Das

This study develops PERSIST-seq and In-line-seq to optimize mRNA stability and translation, finding that in-cell stability is more critical than ribosome load for protein output.

400 citationstop 1%

humanmultiome

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Developmental BiologyDevelopmental CellPeer-reviewedJul 1, 2021

A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies

Gerald C. Tiu, Craig H. Kerr, Craig M. Forester…·Maria Barna

This study identifies a p53-dependent translational program that explains tissue-selective phenotypes in ribosomopathies by regulating 4E-BP1 and altering the translatome.

59 citations

mousestatistical model

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