Author

Leon Wang

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alison GoateiD· 1 shared Ana C. PereiraiD· 1 shared Andrea Pérez ArévaloiD· 1 shared Anna BrightiD· 1 shared Ardem PatapoutianiD· 1 shared Ashley HarlockiD· 1 shared Braxton Riley SchuldtiD· 1 shared Darren J. LipomiiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Alison GoateORCID

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2 papers

Recent·Most cited

APOE4 promotes cerebrovascular fibrosis and amyloid deposition via a pericyte-to-myofibroblast transition

Braxton Riley Schuldt, Dominic Haworth-Staines, Andrea Pérez Arévalo, Diede W. M. Broekaart, Ashley Harlock, Leon Wang, Anna Bright, Georgia Gallagher, Grace Rabinowitz, Alison Goate, Towfique Raj, Ana C. Pereira, Joel Blanchard

This study identifies APOE4-driven pericyte-to-myofibroblast transition in cerebrovascular disease, leading to fibrosis and amyloid deposition, and shows TGF-β inhibition can reverse these effects.

bioRxiv · Sep 4, 2025 · PreprintNeuroscience

A key role of PIEZO2 mechanosensitive ion channel in adipose sensory innervation

Yu Wang, Yunxiao Zhang, Verina H. Leung, Saba Heydari Seradj, Utku M. Sönmez, M. Rocio Servin‐Vences, Shuke Xiao, Xiangyu Ren, Leon Wang, Sassan A Mishkanian, Sejal A Kini, Jonathan Z. Long, Darren J. Lipomi, Ye Li, Ardem Patapoutian

The paper identifies PIEZO2 as a key mechanosensitive ion channel in adipose sensory innervation and shows its role in regulating adipose tissue phenotypes.

Cell Metabolism · Mar 6, 2025Peer-reviewedNeuroscience