Leona H. Gagnon

CellMAGE deconvolves gene expression in multi-parent populations by leveraging known parental genetic contributions, outperforming existing methods in accuracy and efficiency.

The paper identifies genomic loci associated with cellular rhythms in Diversity Outbred mice using QTL mapping and connects them to circadian regulation and complex traits.

This study identifies a shared genetic regulator linking metabolism and addiction-related behavior in mice and humans through a common enhancer regulating Eed/Me3 and EED/ME3.

The paper examines behavioral variation in cocaine self-administration across multiple phases in genetically diverse mouse populations, identifying strain and sex differences and extreme strains for drug intake traits.

The paper identifies genetic loci associated with reversal learning phenotypes in Diversity Outbred mice, revealing a genome-wide significant QTL on chromosome 7.

The paper examines heritability of reward sensitivity and impulsivity traits in inbred mice and finds these traits are independent and heritable.

This study shows that including genetic and sex differences in mice improves the alignment of addiction-related traits with human studies.