Author

Liesbeth Voorbraeck

Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Centre for Alzheimer Research, Karolinska Institutet;

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Zhibai Cao· 2 shared Doste R Mamand· 1 shared Doste Rashid MamandiD· 1 shared Francesca Pozzobon· 1 shared Jesus Alarcon-Gil· 1 shared Jesús Alarcón-GiliD· 1 shared Joana B. Pereira· 1 shared Joana B. PereiraiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Zhibai Cao

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Author profile →

2 papers

Recent·Most cited

Brain mitovesicles undergo stage-specific remodelling during the progression of amyloid-β pathology

Liesbeth Voorbraeck, Jesus Alarcon-Gil, Mite Mijalkov, Massimiliano Passaretti, Zhibai Cao, Doste R Mamand, Sara Garcia-Ptacek, Julianna Kele, Stephanie L. Fowler, Maria Ankarcrona, Joana B. Pereira, Luana Naia

This study shows that mitovesicles from Alzheimer's disease mouse models undergo stage-specific proteomic changes that reflect mitochondrial dysfunction and provide a conserved disease signature in humans.

bioRxiv · Nov 3, 2026 · PreprintNeuroscience

Astrocyte-neuron mitochondrial transfer via mitoEVs supports neuronal energy metabolism and is impaired in early Alzheimer's disease

Liesbeth Voorbraeck, Jesús Alarcón-Gil, Romain Giraud, Francesca Pozzobon, Maria João Pereira, Shubin Guo, Zhibai Cao, Krizia Distefano, Mohammad Hossein Forouzanfar, Oscar P. B. Wiklander, Mite Mijalkov, Joana B. Pereira, Doste Rashid Mamand, Maria Ankarcrona, Luana Naia

This study identifies mitoEV-mediated mitochondrial transfer from astrocytes to neurons as a compromised pathway in early Alzheimer's disease, revealing its role in supporting neuronal energy metabolism.

bioRxiv · Mar 9, 2026 · PreprintNeuroscience