Joana B. Pereira

Astrocyte-neuron mitochondrial transfer via mitoEVs supports neuronal energy metabolism and is impaired in early Alzheimer's disease

This study identifies mitoEV-mediated mitochondrial transfer from astrocytes to neurons as a compromised pathway in early Alzheimer's disease, revealing its role in supporting neuronal energy metabolism.

Diurnal dynamics of multilayer brain networks predict cognitive trajectories in aging

The paper examines diurnal changes in brain network dynamics and their association with cognitive aging and Alzheimer's disease markers.

Quantitative Multicolored Deep Imaging of Human Bones Reveals a Composite Osteo-Sinusoidal Niche for Mesenchymal Stromal Cells.

The paper uses a tissue-clearing protocol to spatially map BM-MSCs in human bones, revealing distinct microenvironment features in young and aged bones.

BRAPH 2: a flexible, open-source, reproducible, community-oriented, easy-to-use framework for network analyses in neurosciences

BRAPH 2 provides a flexible, open-source framework for network analyses in neuroscience with advanced statistical models and deep learning capabilities.

Linking structural and functional changes during aging using multilayer brain network analysis

This study links structural and functional brain changes during aging using multilayer network analysis on diffusion tensor imaging and magnetoencephalography data from the Cam-CAN database, showing associations between structural connectivity and cognitive performance.

Directed brain connectivity identifies widespread functional network changes in Parkinson's disease

This study introduces a directed connectivity method to analyze brain networks in Parkinson's disease, finding widespread functional network changes not detected by undirected methods.

Dendritic spines are lost in clusters in Alzheimers disease

This study uses graph-theory approaches to show that tau pathology in Alzheimer's disease causes clustered dendritic spine loss, not random loss, linking tau to memory deficits through altered spine organization.

Age-related differences in network structure and dynamic synchrony of cognitive control

This study examines age-related differences in brain network structure and dynamic synchrony, linking white matter microstructure to cognitive control performance in older adults.

Fully Bayesian longitudinal unsupervised learning for the assessment and visualization of AD heterogeneity and progression

The paper develops a Bayesian longitudinal clustering framework to identify distinct AD brain atrophy patterns and their progression, revealing heterogeneity in disease progression.

Medial temporal atrophy in preclinical dementia: visual and automated assessment during six year follow-up

The paper assesses longitudinal medial temporal lobe atrophy in preclinical dementia using visual and automated methods over six years, finding that visual ratings correlate with subcortical volumes but have low inter-rater agreement.

BRAPH: A Graph Theory Software for the Analysis of Brain Connectivity

BRAPH is a MATLAB-based software for analyzing brain connectivity using graph theory, enabling structural and functional network analysis in neurological studies.