Author

Linghui Nie

The University of Texas Medical Branch at Galveston

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 1 Approach:experimental assay· 1

Frequent Co-Authors

Annie Tao· 1 shared Charlene Smith-GeateriD· 1 shared Chi-Lin TsaiiD· 1 shared Cornelis J. ElferinkiD· 1 shared Devon F. Pandlebury· 1 shared Francis Leonard· 1 shared John A. TaineriD· 1 shared Keegan M. BushiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Annie Tao

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1 paper

Recent·Most cited

Chromatin remodeler BRG1 recruits huntingtin to repair DNA double-strand breaks in neurons

Subrata Pradhan, Keegan M. Bush, Nan Zhang, RAJ KUMAR PANDITA, Chi-Lin Tsai, Charlene Smith-Geater, Devon F. Pandlebury, Sagar Gaikwad, Francis Leonard, Linghui Nie, Annie Tao, William K. Russell, Subo Yuan, Sanjeev Choudhary, Kenneth S. Ramos, , Partha S. Sarkar

This study identifies a mechanism where HTT recruits BRG1 and NHEJ components to repair transcription-associated DSBs in neurons, and shows that mutant HTT impairs this process, contributing to HD pathology.

bioRxiv · Sep 19, 2024 · PreprintNeuroscience