Author
National Institutes of Health
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Josef Hanke, Sebastian Pujalte Ojeda, Ruoh Wen Cheong…·Michele Vendruscolo
OmniBind predicts small-molecule promiscuity across the human proteome using a neural network, enabling faster early-stage drug screening with improved specificity over affinity alone.
Pilar Álvarez Jerez, Peter Wild Crea, Dhairya Patel…·Cornelis Blauwendraat
The paper investigates the biological impact of GBA1 mutations using multi-omics in isogenic iPSC lines, finding limited overlapping results across cell types and suggesting RNA-based quantitation may not be optimal for characterizing GCase mechanisms.
Darian Williams, Logan M. Glasstetter, Tiffany T. Jong…·Yu Chen
This paper develops high-throughput assays to identify and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase, showing NCGC326 reverses pathological accumulation and synergizes with proteostasis regulators.