Author

Tiffany T. Jong

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Abhijeet KapooriD· 1 shared Alexandra GehrleiniD· 1 shared Andrew N. HoganiD· 1 shared Darian WilliamsiD· 1 shared David J. VocadloiD· 1 shared Ellen SidranskyiD· 1 shared Juan MarugániD· 1 shared Kimberly WongiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Abhijeet KapoorORCID

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1 paper

Recent·Most cited

Development of quantitative high-throughput screening assays to identify, validate, and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase with therapeutic potential for Gaucher disease and Parkinson's disease

Darian Williams, Logan M. Glasstetter, Tiffany T. Jong, Tiffany Chen, Abhijeet Kapoor, Sha Zhu, Yanping Zhu, Raul Calvo, Alexandra Gehrlein, Kimberly Wong, Andrew N. Hogan, David J. Vocadlo, Ravi Jagasia, Juan Marugán, Ellen Sidransky, , Yu Chen

This paper develops high-throughput assays to identify and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase, showing NCGC326 reverses pathological accumulation and synergizes with proteostasis regulators.

Proceedings of the National Academy of Sciences · Oct 10, 2024Peer-reviewedPharmacology & Toxicology