Author

Lois Kent

The Francis Crick Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Mark J. SkeheliD· 2 shared David A BrowniD· 1 shared David BalchiniD· 1 shared Francesca Ester MorrealeiD· 1 shared Grant A. PelloweiD· 1 shared Ilaria Dalla RosaiD· 1 shared Joshua J. DaviesiD· 1 shared Laura KarpauskaiteiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMicrobiology

Mark J. SkehelORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BacPROTACs outperform inhibitors in Mycobacterium tuberculosis

David A Brown, Joshua J. Davies, Selina Fecht, Yujia Zhang, Simone Kunzelmann, Lois Kent, Mark J. Skehel, Francesca Ester Morreale

This study develops BacPROTACs, a new class of antibacterial agents targeting M. tuberculosis, showing improved activity over traditional inhibitors.

bioRxiv · Jun 12, 2026 · PreprintMicrobiology

Molecular determinants of cotranslational chaperone recruitment to nascent p53

Laura Karpauskaite, Tomas B. Voisin, Sarah Maslen, Lois Kent, Grant A. Pellowe, Mark J. Skehel, David Balchin

The paper investigates how chaperones like Hsp70, Hsp90, and TRiC bind to nascent p53 during translation, showing TRiC's specificity and how mutations affect this process.

bioRxiv · Apr 21, 2026 · PreprintBiochemistry

Non-Redundant Roles of Topoisomerase 2α and 2β in the Cytosolic Replication of Vaccinia Virus

Ilaria Dalla Rosa, Lois Kent, Michael Way

This study identifies distinct roles of TOP2A and TOP2B in vaccinia virus replication, showing TOP2A promotes replication while TOP2B suppresses it by forming antiviral granules.

Nucleic Acids Research · Jun 20, 2025Peer-reviewedCell Biology