Author

Lorcan O’Connell

Guy's and St Thomas' NHS Foundation Trust

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Adela Alcolea-Medina· 1 shared Carl Graham· 1 shared Gaia NebbiaiD· 1 shared Helena WinstoneiD· 1 shared Jeffrey SeowiD· 1 shared Jonathan D. EdgeworthiD· 1 shared Katie J. DooresiD· 1 shared Luke B. SnelliD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Adela Alcolea-Medina

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1 paper

Recent·Most cited

Antibody escape drives emergence of diverse spike haplotypes resembling variants of concern in persistent SARS-CoV-2 infections

Luke B. Snell, Suzanne Pickering, Adela Alcolea-Medina, Helena Winstone, Jeffrey Seow, Carl Graham, Lorcan O’Connell, Rahul Batra, Michael H. Malim, Katie J. Doores, Gaia Nebbia, Jonathan D. Edgeworth, Stuart J. D. Neil, Rui Pedro Galão

The paper identifies diverse spike haplotypes in persistent SARS-CoV-2 infections that show immune escape mechanisms similar to variants of concern.

Cell Reports Medicine · Feb 1, 2026Peer-reviewedMicrobiology