Author
University College London
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Konstantinos Stamatiou, Lorena Ligammari, Malki Bothota, Antonia Tsavou, Ezgi Gokhan, Ylenia Cicirò, Mariano F. Zacarías Fluck, Laura Soucek, Arturo Sala, Paola Vagnarelli
The paper identifies a CDCA2-MYC positive feedback loop that promotes cancer cell survival in multiple cancer types.
Open Biology · Mar 11, 2026Peer-reviewedCell Biology
Lucia Cottone, James E. Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Giorgia Gaeta, John C. Christianson, Adrienne Margaret Flanagan, Udo C. T. Oppermann, Adam P. Cribbs
This study identifies ATF4-mediated metabolic stress response as a therapeutic target in chordoma, showing that EPRS inhibitors reduce cell viability and inhibit tumor growth in vivo.
bioRxiv · Feb 27, 2025 · PreprintCancer Biology
Inga Usher, Lorena Ligammari, Sara Ahrabi, Emily Hepburn, Calum Connolly, Gareth L. Bond, Adrienne Margaret Flanagan, Lucia Cottone
The paper describes a workflow for efficient single nucleotide variant editing using CRISPR/Cas9, showing how experimental conditions affect editing efficiency and introducing methods for screening and quality control.
bioRxiv · Nov 12, 2021 · PreprintMolecular Biology
Lucia Cottone, Edward S Hookway, Adam Cribbs, Graham Wells, Patrick Lombard, Lorena Ligammari, Anthony Tumber, Roberto Tirabosco, Fernanda Amary, Tamas Szommer, Catrine Johannson, Paul E Brennan, Nischalan Pillay, Udo Oppermann, Adrienne M Flanagan
This study shows that inhibiting H3K27 demethylases reduces TBXT expression and kills chordoma cells by altering epigenetic marks and gene expression.
bioRxiv · Oct 1, 2018 · PreprintCancer Biology