Author

Lydia Paulsen

German Center for Neurodegenerative Diseases

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Organism:human· 1 Organism:mouse· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

André Hossinger· 2 shared Ina Maja VorbergiD· 2 shared Philip DenneriD· 2 shared Stefanie-Elisabeth Heumüller· 2 shared Adalbert KrawczykiD· 1 shared Annika Hornberger· 1 shared Barbara G. Klupp· 1 shared Dominik StappertiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

André Hossinger

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The core herpes simplex-1 fusion complex drives cell-to-cell spreading of pathological Tau

Stefanie-Elisabeth Heumüller, Mikhail E. Sushkin, Elisa Sánchez-Sendín, André Hossinger, Dominik Stappert, Nazlican Altinisik, Louisa Seiwert, Lydia Paulsen, Adalbert Krawczyk, Barbara G. Klupp, Thomas C. Mettenleiter, Philip Denner, Harald Prüß, Ina Maja Vorberg

This study shows HSV-1 fusion proteins enable cell-to-cell spread of pathological Tau, suggesting latent HSV-1 infection may contribute to neurodegenerative disease progression.

bioRxiv · Jan 21, 2026 · PreprintNeuroscience

Highly efficient intercellular spreading of protein misfolding mediated by viral ligand - receptor interactions

Shu Liu, André Hossinger, Stefanie-Elisabeth Heumüller, Annika Hornberger, Oleksandra Buravlova, Katerina Konstantoulea, Stephan A. Müller, Lydia Paulsen, Frédéric Rousseau, Joost W. H. Schymkowitz, Stefan F. Lichtenthaler, Manuela Neumann, Philip Denner, Ina Maja Vorberg

The paper shows viral ligand-receptor interactions enhance the spread of protein misfolding via extracellular vesicles and direct cell contact.

Nature Communications · Oct 19, 2021Peer-reviewedNeuroscience