Author

Mélanie Laporte

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Blandine MoneliD· 2 shared Agnès Fortun· 1 shared Ana Cecília A. RoqueiD· 1 shared Anna P. McLean· 1 shared Arménio Jorge Moura BarbosaiD· 1 shared Barbara MouratouiD· 1 shared Bruce D. WalkeriD· 1 shared Cyril PlanchaisiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Blandine MonelORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Optimized pipeline for generating highly potent neutralizing Affitins: application to SARS-CoV-2 spike protein

Thomas Maurice, Mélanie Laporte, Nicolas Barquilla, Agnès Fortun, Klára Echasserieau, Florence Guivel‐Benhassine, Arménio Jorge Moura Barbosa, Pauline Cossard, Cyril Planchais, François Anna, Pierre Charneau, Hugo Mouquet, Ana Cecília A. Roque, Olivier Schwartz, Barbara Mouratou, , Frédéric Pecorari

The paper develops a pipeline to generate potent Affitins targeting SARS-CoV-2 spike protein RBD, achieving high neutralization potency with IC50 values as low as 0.8 pM.

International Journal of Biological Macromolecules · Nov 28, 2025Peer-reviewedBiochemistry

SLAMF6 enables efficient attachment, synapse formation, and killing of HIV-1-infected CD4+ T cells by virus-specific CD8+ T cells

Blandine Monel, Pedro A. Lamothe, James Meyo, Anna P. McLean, Raymond Quiñones‐Alvarado, Mélanie Laporte, Julie Boucau, Bruce D. Walker, Daniel G. Kavanagh, Wilfredo F. García-Beltrán, Yovana Pacheco

This study shows that SLAMF6 is essential for CD8+ T cells to form synapses and kill HIV-1-infected CD4+ T cells, as blocking SLAMF6 reduces conjugate formation and cytotoxicity.

bioRxiv · Jan 20, 2025 · PreprintImmunology