Author

M. A. DeJesus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:multiple species· 1 Approach:statistical model· 1

Frequent Co-Authors

J. M. Rock· 3 shared N. C. Poulton· 2 shared Z. A. Azadian· 2 shared A. Jinich· 1 shared A. Zaveri· 1 shared B. Bosch· 1 shared C. G. Roberts· 1 shared C. M. Sassetti· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

J. M. Rock

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Author profile →

3 papers

Recent·Most cited

Beyond antibiotic resistance: the whiB7 transcription factor coordinates an adaptive response to alanine starvation in mycobacteria

N. C. Poulton, M. A. DeJesus, V. Munsamy-Govender, C. G. Roberts, Z. A. Azadian, B. Bosch, K. M. Lin, S. Li, J. M. Rock

This study identifies signals that activate the whiB7 stress response in mycobacteria, revealing its role in coordinating an adaptive response to alanine starvation.

bioRxiv · Jun 2, 2023 · PreprintMicrobiology

Mutations in rv0678 confer low-level resistance to benzothiazinone DprE1 inhibitors in M. tuberculosis

N. C. Poulton, Z. A. Azadian, M. A. DeJesus, J. M. Rock

This study identifies rv0678 mutations as a mechanism of resistance to benzothiazinone DprE1 inhibitors in M. tuberculosis, showing cross-resistance to BTZ043 and PBTZ169.

bioRxiv · Jun 29, 2022 · PreprintMicrobiology

The Mycobacterium tuberculosis transposon sequencing database (MtbTnDB): a large-scale guide to genetic conditional essentiality

A. Jinich, A. Zaveri, M. A. DeJesus, E. Flores-Bautista, R. Almada-Monter, C. M. Smith, C. M. Sassetti, J. M. Rock, S. Ehrt, D. Schnappinger, T. R. Ioerger, K. Y. Rhee

The paper builds MtbTnDB, a database of Mtb TnSeq screens, enabling comparison of genetic essentiality across conditions and analysis of gene function.

bioRxiv · Mar 5, 2021 · PreprintMicrobiology