Author

P. F. Kiser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:non-human primate· 2 Research Focus:host-pathogen & immune response· 1 Organism:rat· 1

Frequent Co-Authors

J. Su· 2 shared T. J. Hope· 2 shared A. Martin· 1 shared A. Ott· 1 shared B. Grasperge· 1 shared C. M. Cain· 1 shared D. Karunakaran· 1 shared D. Maric· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPharmacology & Toxicology

J. Su

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2 papers

Recent·Most cited

Simultaneous in vivo Pharmacokinetics and Pharmacodynamics of TDF Intravaginal Ring during High-dose Vaginal SHIV Challenge in Pigtail Macaques

K. Klotnik Halavaty, A. Ott, D. Maric, J. Su, E. Matias, E. J. Allen, A. Martin, L. E. Pereira, F. Deyounks, J. Smith, P. F. Kiser, T. J. Hope

This study examines TFV distribution and protection efficacy of a TDF IVR in macaques during high-dose SIV challenge, finding uneven TFV distribution and incomplete protection.

bioRxiv · Jun 29, 2021 · PreprintPharmacology & Toxicology

A Subcutaneous Implant of Tenofovir Alafenamide Fumarate Causes Local Inflammation and Tissue Necrosis in Rabbits and Macaques

J. Su, S. M. Simpson, S. Sung, E. Bryndza-Tfaily, R. S. Veazey, M. A. Marzinke, J. Qiu, D. Watrous, L. Widanapathirana, E. Pearson, M. M. Peet, D. Karunakaran, B. Grasperge, G. Dobek, C. M. Cain, , P. F. Kiser

This study evaluates a subcutaneous TAF implant for HIV prevention, finding it achieves sustained drug levels but causes severe local inflammation and necrosis in rabbits and macaques.

bioRxiv · Sep 19, 2019Pharmacology & Toxicology