Author

N. Heinemann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Richter· 3 shared C. Drosten· 3 shared D. Niemeyer· 3 shared C. Goffinet· 2 shared J. Emanuel· 2 shared J. Heinze· 2 shared J. Jansen· 2 shared J. Papies· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

A. Richter

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Pharmacological inhibition of bromodomain and extra-terminal proteins induces NRF-2-mediated inhibition of SARS-CoV-2 replication and is subject to viral antagonism

B. Mhlekude, D. Postmus, J. Weiner, S. Stenzel, F. J. Zapatero-Belinchon, R. Olmer, J. Jansen, A. Richter, J. Heinze, N. Heinemann, B. Muhlemann, S. Schroeder, T. C. Jones, M. A. Muller, C. Drosten, , C. Goffinet

This study shows JQ-1 inhibits SARS-CoV-2 replication via NRF-2 activation but is counteracted by viral antagonism, leading to transient antiviral effects.

bioRxiv · Sep 22, 2022 · PreprintMicrobiology

Staphylococcus aureus activates the Aryl Hydrocarbon Receptor in Human Keratinocytes

E.-L. Stange, F. Rademacher, K. A. Drerup, N. Heinemann, L. Möbus, R. Gläser, J. Harder

This study shows that Staphylococcus aureus activates the Aryl Hydrocarbon Receptor (AhR) in human keratinocytes, leading to cytokine production and highlighting AhR as a novel sensor for S. aureus.

bioRxiv · Jan 5, 2022 · PreprintImmunology

Post-entry, spike-dependent replication advantage of B.1.1.7 and B.1.617.2 over B.1 SARS-CoV-2 in an ACE2-deficient human lung cell line

D. Niemeyer, S. Schroeder, K. Friedmann, F. Weege, J. Trimpert, A. Richter, S. Stenzel, J. Jansen, J. Emanuel, J. Kazmierski, F. Pott, L. M. Jeworowski, R. Olmer, M.-C. Jaboreck, B. Tenner, , C. Drosten

The paper shows that B.1.1.7 and B.1.617.2 SARS-CoV-2 variants have a replication advantage over B.1 in ACE2-deficient lung cells, suggesting reliance on alternative cellular factors.

bioRxiv · Oct 20, 2021 · PreprintMicrobiology

Analysis of SARS-CoV-2-controlled autophagy reveals spermidine, MK-2206, and niclosamide as putative antiviral therapeutics

N. C. Gassen, J. Papies, T. Bajaj, F. Dethloff, J. Emanuel, K. Weckmann, D. E. Heinz, N. Heinemann, M. Lennarz, A. Richter, D. Niemeyer, V. M. Corman, P. Giavalisco, C. Drosten, M. A. Muller

This study identifies spermidine, MK-2206, and niclosamide as potential antiviral therapeutics by enhancing autophagy against SARS-CoV-2 in vitro.

bioRxiv · Apr 15, 2020Microbiology