Author

M. A. Sartor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

D. C. Dolinoy· 2 shared F. J. Nunez· 2 shared J. A. Colacino· 2 shared K. Banerjee· 2 shared K. Wang· 2 shared M. Ljungman· 2 shared P. Kadiyala· 2 shared P. R. Lowenstein· 2 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersPharmacology & Toxicology

D. C. Dolinoy

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Epigenetic reprogramming of autophagy leads to uncovering a novel therapeutic target for mutant IDH1 astrocytomas

F. J. Nunez, K. Banerjee, A. A. Mujeeb, A. Mauser, C. E. Tronrud, Z. Zhu, S. Raghuram, M. R. Sheth, J. A. Pena Agudelo, J. Zelaya, A. Taher, P. Kadiyala, S. V. Carney, M. B. Garcia-Fabiani, A. Comba, , M. Castro

This study identifies autophagy as a critical survival pathway in mIDH1 gliomas and shows that inhibiting autophagy enhances radiosensitivity and tumor regression in preclinical models.

bioRxiv · Mar 8, 2024 · PreprintCancer Biology

Effects of Developmental Lead and Phthalate Exposures on DNA Methylation in Adult Mouse Blood, Brain, and Liver Identifies Tissue- and Sex-Specific Changes with Implications for Genomic Imprinting

R. K. Morgan, K. Wang, L. K. Svoboda, C. A. Rygiel, C. Lalancette, R. Cavalcante, M. S. Bartolomei, R. D. Prasasya, K. Neier, B. P. Perera, T. R. Jones, J. A. Colacino, M. A. Sartor, D. C. Dolinoy

This study examines DNA methylation changes in mouse tissues due to lead and phthalate exposure, identifying tissue- and sex-specific DMRs and their association with genomic imprinting.

bioRxiv · Sep 29, 2023 · PreprintPharmacology & Toxicology

Data Fusion by Matrix Completion for Exposome Target Interaction Prediction

K. Wang, N. Kim, M. Bagherian, K. Li, E. Chou, J. A. Colacino, D. C. Dolinoy, M. A. Sartor

This study introduces a matrix completion method to predict chemical-target interactions, achieving high accuracy and demonstrating its utility for prioritizing environmental chemicals.

bioRxiv · Aug 24, 2022 · PreprintPharmacology & Toxicology

Zinc Finger MYND-Type Containing 8 (ZMYND8) is epigenetically regulated in mutant Isocitrate Dehydrogenase 1 (IDH1) glioma to promote radioresistance

S. V. Carney, K. Banerjee, A. Mujeeb, B. Zhu, S. Haase, M. L. Varela, P. Kadiyala, C. Tronrud, Z. Zhu, D. Mukherji, P. Gorla, R. Tagett, F. J. Nunez, M. Luo, W. Lou, , M. G. Castro

This paper identifies ZMYND8 as a gene epigenetically regulated by mIDH1 that promotes radioresistance in glioma cells, and shows its knockdown enhances radiosensitivity.

bioRxiv · Jun 10, 2022Cancer Biology

Cadmium exposure inhibits branching morphogenesis and causes alterations consistent with HIF-1α inhibition in human primary breast organoids

S. A. Rocco, L. Koneva, L. Y. M. Middleton, T. Thong, S. Solanki, S. Karram, K. Nambunmee, C. Harris, L. S. Rozek, M. A. Sartor, Y. M. Shah, J. Colacino

This study shows cadmium exposure inhibits branching morphogenesis and HIF-1α activity in human breast organoids, suggesting it disrupts mammary gland development rather than promoting cancer.

bioRxiv · Nov 3, 2017Pharmacology & Toxicology