Author

S. V. Carney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

P. Kadiyala· 3 shared P. R. Lowenstein· 3 shared A. Schwendeman· 2 shared F. J. Nunez· 2 shared K. Banerjee· 2 shared M. A. Sartor· 2 shared M. Castro· 2 shared M. Ljungman· 2 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

P. Kadiyala

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Author profile →

3 papers

Recent·Most cited

Epigenetic reprogramming of autophagy leads to uncovering a novel therapeutic target for mutant IDH1 astrocytomas

F. J. Nunez, K. Banerjee, A. A. Mujeeb, A. Mauser, C. E. Tronrud, Z. Zhu, S. Raghuram, M. R. Sheth, J. A. Pena Agudelo, J. Zelaya, A. Taher, P. Kadiyala, S. V. Carney, M. B. Garcia-Fabiani, A. Comba, , M. Castro

This study identifies autophagy as a critical survival pathway in mIDH1 gliomas and shows that inhibiting autophagy enhances radiosensitivity and tumor regression in preclinical models.

bioRxiv · Mar 8, 2024 · PreprintCancer Biology

Zinc Finger MYND-Type Containing 8 (ZMYND8) is epigenetically regulated in mutant Isocitrate Dehydrogenase 1 (IDH1) glioma to promote radioresistance

S. V. Carney, K. Banerjee, A. Mujeeb, B. Zhu, S. Haase, M. L. Varela, P. Kadiyala, C. Tronrud, Z. Zhu, D. Mukherji, P. Gorla, R. Tagett, F. J. Nunez, M. Luo, W. Lou, , M. G. Castro

This paper identifies ZMYND8 as a gene epigenetically regulated by mIDH1 that promotes radioresistance in glioma cells, and shows its knockdown enhances radiosensitivity.

bioRxiv · Jun 10, 2022Cancer Biology

Inhibition of 2-Hydroxyglutrate Elicits Metabolic-reprograming and Mutant IDH1 Glioma Immunity

P. Kadiyala, S. V. Carney, J. C. Gauss, M. Garcia-Fabiani, F. Nunez, F. M. Nunez, M. Alghamri, Y. Liu, M. Yu, D. Li, M. Edwards, J. J. Moon, A. Schwendeman, P. R. Lowenstein, M. Castro

This study shows that inhibiting 2-hydroxyglutarate in mIDH1 gliomas with ATRX/TP53 inactivation improves survival and induces anti-tumor immunity through immunological memory and reduced T-cell exhaustion.

bioRxiv · May 11, 2020 · PreprintImmunology