Author

J. Colacino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 3 Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:differential expression· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Y. M. Shah· 2 shared A. Kahana· 1 shared A. Wood· 1 shared B. Lavoie· 1 shared B. S. Nelson· 1 shared C. A. Lyssiotis· 1 shared C. E. Wobus· 1 shared C. Harris· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

Y. M. Shah

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Glucose-6-phosphate dehydrogenase deficiency accelerates pancreatic acinar-to-ductal metaplasia

M. D. Radyk, B. S. Nelson, C. J. Halbrook, A. Wood, B. Lavoie, L. Salvatore, G. Corfas, J. Colacino, Y. M. Shah, H. C. Crawford, C. A. Lyssiotis

This study shows that G6PD deficiency accelerates pancreatic acinar-to-ductal metaplasia by enhancing NADPH production for ROS management, highlighting a metabolic role in early tumorigenesis.

bioRxiv · Nov 6, 2023 · PreprintCancer Biology

Human norovirus efficiently replicates in differentiated 3D-human intestinal enteroids

C. Mirabelli, N. Santos-Ferreira, M. G. Gillilland, R. J. Cieza, J. Colacino, J. Z. Sexton, S. Taube, J. Rocha-Pereira, C. E. Wobus

This paper develops a simplified protocol for infecting 3D-human intestinal enteroids with human norovirus, showing improved infection efficiency and host response analysis.

bioRxiv · Jun 9, 2022Microbiology

Cellular Pharmacology of Curcumin With and Without Piperine

R. I. Mahran, P. Shu, J. Colacino, M. M. Hagras, D. Sun, D. E. Brenner

This study investigates how piperine affects curcumin's cellular effects in breast cells, finding synergistic anti-carcinogenic effects without altering curcumin concentrations.

bioRxiv · Jul 14, 2021 · PreprintPharmacology & Toxicology

Identifying the Link Between Chemical Exposures and Breast Cancer in African American Women via ToxCast High Throughput Screening Data

K. Polemi, V. K. Nguyen, J. Heidt, A. Kahana, O. Jolliet, J. Colacino

This study identifies chemicals with breast cancer-related biological activity that are disproportionately exposed in African American women using ToxCast data and biomonitoring.

bioRxiv · Jan 22, 2021Pharmacology & Toxicology

DNA methylation signature of smoking in lung cancer is enriched for exposure signatures in newborn and adult blood.

K. M. Bakulski, J. Dou, N. Lin, S. London, J. Colacino

The paper identifies DNA methylation signatures of smoking in lung cancer and finds significant overlap with signatures in newborn and adult blood.

bioRxiv · Jun 26, 2018Cancer Biology

Cadmium exposure inhibits branching morphogenesis and causes alterations consistent with HIF-1α inhibition in human primary breast organoids

S. A. Rocco, L. Koneva, L. Y. M. Middleton, T. Thong, S. Solanki, S. Karram, K. Nambunmee, C. Harris, L. S. Rozek, M. A. Sartor, Y. M. Shah, J. Colacino

This study shows cadmium exposure inhibits branching morphogenesis and HIF-1α activity in human breast organoids, suggesting it disrupts mammary gland development rather than promoting cancer.

bioRxiv · Nov 3, 2017Pharmacology & Toxicology