Author

M. Alqazzaz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Hutchinson· 1 shared A. Seitova· 1 shared C. Arrowsmith· 1 shared C. H. Arrowsmith· 1 shared C. P. Alvarez· 1 shared C. Secker· 1 shared D. Barsyte-Lovejoy· 1 shared E. C. Adamson· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. Hutchinson

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Author profile →

2 papers

Recent·Most cited

Epigenetic vulnerabilities of leukemia harboring inactivating EZH2 mutations

M. Alqazzaz, G. Luciani, V. Vu, R. M. Machado, M. M. Szewczyk, E. C. Adamson, S. Cheon, C. Arrowsmith, M. D. Minden, D. Barsyte-Lovejoy

This study identifies epigenetic vulnerabilities in AML and MDS/MPN with EZH2 mutations, showing increased sensitivity to EZH2 and EED inhibitors and upregulation of cell death pathways.

bioRxiv · Nov 20, 2023Cancer Biology

Expanding the Huntingtons disease research toolbox; validated huntingtin subdomain constructs for biochemical and structural investigation of the huntingtin protein

M. G. Alteen, J. C. Deme, C. P. Alvarez, P. Loppnau, A. Hutchinson, A. Seitova, R. Chandrasekaran, E. Silva Ramos, C. Secker, M. Alqazzaz, E. E. Wanker, S. M. Lea, C. H. Arrowsmith, R. J. Harding

This paper develops validated HTT subdomain constructs for biochemical and structural studies of huntingtin protein interactions and function.

bioRxiv · Nov 21, 2022Biochemistry