M. Ashraf

Phenotypic Switching of Vascular Smooth Muscle Cells in Duchenne Muscular Dystrophy

This study investigates how dystrophin deficiency in vascular smooth muscle cells (VSMCs) leads to phenotypic switching and mitochondrial dysfunction in DMD, identifying potential transcription factors involved.

Patient and cell-type specific hiPSC-modeling of a truncating titin variant associated with atrial fibrillation

This study uses patient-derived iPSC-CMs to show that a titin truncating variant increases arrhythmia susceptibility and disrupts sarcomere structure in both atrial and ventricular tissues.

An in vitro assessment of anti-SARS-CoV-2 activity of oral preparations of iodine complexes (RENESSANS)

This study assesses the in vitro anti-SARS-CoV-2 activity of iodine complex oral formulations, finding that higher concentrations show significant inhibition of viral replication and cytopathic effects.

Evaluation of cytotoxic, antiviral effect and mutagenic potential of a micronutrient combination in vitro cell culture

This study evaluates the cytotoxic, antiviral, and mutagenic effects of a micronutrient combination in vitro using chicken embryo fibroblasts and the Ames test.

Human iPS Cells Derived Skeletal Muscle Progenitor Cells Promote Myoangiogenesis and Restore Dystrophin in Duchenne Muscular Dystrophic Mice

This study generates muscle progenitor cells from hiPSCs using givinostat and shows they restore dystrophin and promote myoangiogenesis in DMD mice.

Agronomic, physiological and molecular characterization of rice mutants revealed key role of ROS and catalase in high temperature stress tolerance

This study identifies heat-tolerant rice mutants and key molecular factors like catalase and ROS regulation that contribute to high temperature stress tolerance.

Solid State High Throughput Screening Microscopy

The paper introduces a solid state high throughput screening microscopy system that captures images of multiple spatially separated samples rapidly and efficiently without mechanical movement.