Author

M. Barkoulas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Approach:microscopy & imaging analysis· 2 Research Focus:clustering· 1

Frequent Co-Authors

M. Grover· 3 shared M. Hintze· 2 shared S. S. Gang· 2 shared C. Constantinou· 1 shared C. Dunsby· 1 shared D. C. Ekiert· 1 shared D. Raman· 1 shared E. Garcia· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersImmunology

M. Grover

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Impairment of the SKN-1A/NRF1 proteasome surveillance pathway triggers tissue-specific protective immune responses against distinct natural pathogens in C. elegans.

M. Grover, S. S. Gang, E. Troemel, M. Barkoulas

bioRxiv · Aug 22, 2023 · PreprintImmunology

A receptor tyrosine kinase regulated by the transcription factor VAB-3/PAX6 pairs with a pseudokinase to trigger immune signalling upon oomycete recognition in C. elegans

F. Drury, M. Grover, M. Hintze, J. Saunders, M. K. Fasseas, C. Constantinou, M. Barkoulas

This study identifies receptor tyrosine kinase OLD-1 and pseudokinase FLOR-1 as key components of oomycete recognition in C. elegans, regulated by VAB-3/PAX-6 and forming a genetic cluster with chil genes.

bioRxiv · Dec 15, 2022 · PreprintImmunology

A pals-25 gain-of-function allele triggers systemic resistance against natural pathogens of C. elegans

S. S. Gang, M. Grover, K. C. Reddy, D. Raman, Y.-T. Chang, D. C. Ekiert, M. Barkoulas, E. R. Troemel

This paper identifies a PALS-25 gain-of-function mutant in C. elegans that activates immune responses against both epidermal and intestinal pathogens through cross-tissue signaling.

bioRxiv · Jun 28, 2022Immunology

Single-shot phase contrast microscopy using polarisation-resolved differential phase contrast

R. Kalita, W. Flanagan, J. Lightley, S. Kumar, Y. Alexandrov, E. Garcia, M. Hintze, M. Barkoulas, C. Dunsby, P. M. W. French

The paper introduces a single-shot differential phase microscopy technique using a polarisation-sensitive camera to simultaneously acquire images for phase gradient and quantitative phase calculations.

Journal of Biophotonics · Sep 6, 2021Peer-reviewedBiophysics