Distinct cell death pathways induced by granzymes collectively protect against intestinal Salmonella infection
A. S. Chawla, M. Vandereyken, M. Arias, L. Santiago, D. Dikovskaya, C. Nguyen, N. Skariah, N. Wenner, N. Golovchenko, S. Thomson, E. Ondari, M. Garzon-Tituana, C. J. Anderson, M. Bergkessel, J. C. D. Hinton, , M. Swamy
This study shows that granzymes A and B use distinct cell death pathways to protect against intestinal Salmonella infection by balancing bacterial growth and translocation.
bioRxiv · Nov 7, 2021Immunology