Author

A. S. Chawla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Pasare· 2 shared M. Swamy· 2 shared N. Skariah· 2 shared A. Chervonsky· 1 shared A. Copland· 1 shared A. George· 1 shared A. Jain· 1 shared A. Mukherjee· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

C. Pasare

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Author profile →

4 papers

Recent·Most cited

Conserved developmental rewiring of the TCR signalosome drives tolerance in innate-like lymphocytes

A. S. Chawla, H. J. Watt, S. A. Schattgen, N. Skariah, I. Saha, K. Warrick, M. Ogawa, F. Lamoliatte, J. Strid, A. Copland, S. Pryde, E. Knatko, K. D. Rasmussen, K. Kikuchi, P. G. Thomas, , M. Swamy

The paper identifies a conserved mechanism, RePrESS, by which autoreactive innate-like T cells maintain tolerance through rewiring of the TCR signalosome.

bioRxiv · Sep 1, 2023 · PreprintImmunology

Distinct cell death pathways induced by granzymes collectively protect against intestinal Salmonella infection

A. S. Chawla, M. Vandereyken, M. Arias, L. Santiago, D. Dikovskaya, C. Nguyen, N. Skariah, N. Wenner, N. Golovchenko, S. Thomson, E. Ondari, M. Garzon-Tituana, C. J. Anderson, M. Bergkessel, J. C. D. Hinton, , M. Swamy

This study shows that granzymes A and B use distinct cell death pathways to protect against intestinal Salmonella infection by balancing bacterial growth and translocation.

bioRxiv · Nov 7, 2021Immunology

T cells instruct dendritic cells to produce inflammasome independent IL-1β causing systemic inflammation

A. Jain, R. A. Irizarry-Caro, A. S. Chawla, N. H. Philip, K. R. Carroll, J. Katz, A. Oberst, A. Chervonsky, C. Pasare

This study identifies a T cell-instructed, inflammasome-independent pathway of IL-1β production in dendritic cells that drives systemic inflammation in autoimmune diseases.

bioRxiv · Nov 26, 2018 · PreprintImmunology

Cell-intrinsic genetic regulation of peripheral memory-phenotype T cell frequencies

A. S. Chawla, P. Kanodia, A. Mukherjee, V. Jain, G. Kaur, P. Coshic, K. Chatterjee, N. Wadhwa, U. C. M. Natchu, S. Sopory, S. Bhatnagar, P. P. Majumder, A. George, V. Bal, S. Rath, S. B. Prabhu

The paper shows memory T cell frequencies are genetically regulated and stable over time, while recently activated cells are influenced by environmental factors.

bioRxiv · Jun 25, 2018Immunology