S. Bansal

Automated Skin Lesion Detection and Prevalence Estimation in Tamanend's Bottlenose Dolphins

This paper develops a machine learning model to detect skin lesions in bottlenose dolphins and estimates lesion prevalence, finding high model accuracy and a positive relationship between lesion presence and gregariousness.

HIF-1 activated by PIM1 assembles a pathological transcription complex and regulon that drives JAK2V617F MPN disease

This study identifies that HIF-1 activation by PIM1 in JAK2V617F-MPNs drives non-canonical transcription complex formation and disease progression.

Wolbachia incompatible insect technique program optimization over large spatial scales using a process-based model of mosquito metapopulation dynamics

This paper optimizes Wolbachia IIT programs by simulating spatial-temporal mosquito metapopulation dynamics, showing that reducing release frequency and redistributing mosquitoes can lower resource use without compromising efficacy.

FLT3 is genetically essential for ITD-mutated leukemic stem cells but dispensable for human hematopoietic stem cells

This study shows FLT3 is essential for ITD-mutated leukemic stem cells but not for normal hematopoietic stem cells, supporting targeted therapies for AML.

White adipose tissue remodeling in Little Brown Myotis (Myotis lucifugus) with white-nose syndrome

This study compares white adipose tissue lipid composition between WNS-susceptible and resistant bat species, finding differential lipid profiles and WAT remodeling in infected susceptible bats.

Metabolic interactions underpinning high methane fluxes across terrestrial freshwater wetlands

The paper integrates multi-omics data from wetlands to link microbial communities to methane fluxes, identifying conserved genera and metabolic interactions that influence emissions.

Single-cell transcriptional mapping reveals genetic and non-genetic determinants of aberrant differentiation in AML

The paper constructs a reference atlas of human hematopoiesis and maps AML differentiation patterns, revealing genetic and non-genetic factors driving aberrant differentiation in leukemia.

Breathing in sync: how a social behavior structures respiratory epidemic risk in bottlenose dolphins

This study examines how social breathing behavior in bottlenose dolphins influences respiratory virus transmission risk by analyzing contact patterns and demographic differences.

KLRG1 marks tumor-infiltrating CD4 T cell subsets associated with tumor progression and immunotherapy response

The paper identifies KLRG1-expressing CD4 T cell subsets linked to tumor progression and immunotherapy response using longitudinal flow cytometry and machine learning.

Pathogen transmission modes determine contact network structure, altering other pathogen characteristics

The paper shows that contact network structure, shaped by transmission modes, influences pathogen traits needed for success in different transmission strategies.

Rapid range shifts in African Anopheles mosquitoes over the last century

This study tracks elevation and latitudinal range shifts of African malaria mosquitoes over the last century, finding average annual gains of 6.5 meters in elevation and 4.7 kilometers poleward in southern limits.

Borrowing ecological theory to infer interactions between sensitive and resistant breast cancer cell populations

The paper uses ecological theory and in-vitro data to infer interactions between resistant and sensitive breast cancer cell populations, finding a net mutualistic interaction and suggesting adaptive treatment strategies.

An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure

This study optimizes urinary extracellular vesicle isolation methods and detects radiation-induced metabolomic changes using mass spectrometry.

A cellular hierarchy framework for understanding heterogeneity and predicting drug response in AML

This study identifies a cellular hierarchy framework in AML that links disease heterogeneity with drug response and develops a 7-gene biomarker predictive of drug sensitivity.

NAD metabolism modulates inflammation and mitochondria function in diabetic kidney disease

This study shows that nicotinamide riboside (NR) improves mitochondrial function and reduces inflammation in diabetic kidney disease by enhancing NAD metabolism and inhibiting the cGAS-STING pathway.

The epidemiology and genomics of a virulent emerging fungal pathogen in an Australian reptile

The paper investigates the epidemiology and genomics of Nannizziopsis barbatae, a virulent fungal pathogen threatening Australian reptiles, showing its spread and virulence features.

A multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells.

Development of A Decellularized Meniscus Matrix-Based Nanofibrous Scaffold for Meniscus Tissue Engineering

This paper develops a nanofibrous scaffold using decellularized meniscus matrix and synthetic polymers to enhance meniscus cell function and matrix production.

PRAK-03202: A triple antigen VLP vaccine candidate against SARS CoV-2

This paper develops a triple antigen VLP vaccine candidate, PRAK-03202, against SARS-CoV-2 and shows it induces neutralizing antibodies and Th1 immune responses in mice.

Fine-scale spatial patterns of wildlife disease are common and understudied

This study identifies common fine-scale spatial patterns in wildlife disease across multiple systems and highlights the need for more spatial analysis in disease ecology.

Iota carrageenan and xylitol inhibit SARS-CoV-2 in Vero cell culture

This study tests three nasal spray formulations against SARS-CoV-2 in Vero cells, finding iota-carrageenan and xylitol inhibit the virus.

Social fluidity mobilizes contagion in human and animal populations

The paper models social fluidity's impact on disease transmission in human and animal populations, showing density- or frequency-dependent transmission based on social behavior.

Negative density-dependent parasitism in a group-living carnivore

The paper investigates how host density affects parasite infection in European badgers, finding negative density dependence in four out of five parasite taxa.

Multi-Antigenic Virus-like Particle of SARS CoV-2 produced in Saccharomyces cerevisiae as a vaccine candidate

The paper reports the production of a multi-antigenic SARS CoV-2 virus-like particle (VLP) in Saccharomyces cerevisiae as a vaccine candidate, confirmed by TEM and analytical data.

Climate change will drive novel cross-species viral transmission

The paper predicts climate change will drive 4,000 times more novel cross-species viral transmission by 2070, mainly through range-shifting mammals like bats and rodents.

A multi-species repository of social networks

The paper introduces a multi-species repository of social networks containing over 650 networks from 47 species, facilitating comparative studies across taxonomic groups.