Author

M. D. Jain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

F. L. Locke· 2 shared A. J. Griswold· 1 shared B. Evernden· 1 shared B. Ziccheddu· 1 shared C. A. Coughlin· 1 shared F. Maura· 1 shared G. C. Wallace· 1 shared H. Alhaddad· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

F. L. Locke

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Branched-chain keto acids promote an immune-suppressive and neurodegenerative microenvironment in leptomeningeal disease

M. L. Khaled, Y. Ren, R. Kundalia, H. Alhaddad, Z. Chen, G. C. Wallace, B. Evernden, O. E. Ospina, M. Hall, M. Liu, L. N. F. Darville, V. Izumi, Y. A. Chen, S. Pilon-Thomas, P. A. Stewart, , I. Smalley

This study identifies branched-chain keto acid accumulation in leptomeningeal disease CSF, showing immune suppression and neurodegeneration, and shows that reducing BCKA improves outcomes in mouse models.

bioRxiv · Dec 18, 2023 · PreprintCancer Biology

Genomic drivers of large B-cell lymphoma resistance to CD19 CAR-T therapy

M. D. Jain, B. Ziccheddu, C. A. Coughlin, R. Faramand, A. J. Griswold, K. M. Reid, O. Landgren, F. L. Locke, F. Maura, M. L. Davila, J. H. Schatz

This study identifies genomic factors associated with resistance to CD19 CAR-T therapy in large B-cell lymphoma by analyzing whole genome sequencing data from treated patients.

bioRxiv · Aug 25, 2021 · PreprintCancer Biology