Author

M. E. Zamora

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 4 Approach:experimental assay· 4 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

J. S. Brenner· 4 shared J. W. Myerson· 4 shared O. A. Marcos-Contreras· 4 shared J. Nong· 3 shared S. Omo-Lamai· 3 shared E. Arguiri· 2 shared J. Wu· 2 shared M. N. Patel· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersBioengineering

J. S. Brenner

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A combination of physicochemical tropism and affinity moiety targeting of lipid nanoparticles enhances organ targeting

M. E. Zamora, S. Omo-Lamai, M. N. Patel, J. Wu, E. Arguiri, V. Muzykantov, J. W. Myerson, O. A. Marcos-Contreras, J. S. Brenner

This paper combines affinity moiety targeting and physicochemical tropism in lipid nanoparticles to enhance organ targeting, showing improved specificity and uptake in lungs and brain.

bioRxiv · Nov 21, 2023Bioengineering

Physicochemical Targeting of Lipid Nanoparticles to the Lungs Induces Clotting: Mechanisms and Solutions

S. Omo-Lamai, M. E. Zamora, M. N. Patel, J. Wu, J. Nong, Z. Wang, A. Peshkova, L. S. Chase, E.-O. Essien, V. Muzykantov, O. A. Marcos-Contreras, J. W. Myerson, J. S. Brenner

This study identifies thrombosis as a risk of lung-targeted cationic lipid nanoparticles and proposes solutions to mitigate clotting without compromising targeting.

bioRxiv · Jul 21, 2023Bioengineering

Targeting lipid nanoparticles to the blood brain barrier to ameliorate acute ischemic stroke

J. Nong, P. M. Glassman, S. Reyes-Esteves, H. C. Descamps, V. V. Shuvaev, R. Y. Kiseleva, T. E. Papp, M.-G. Alameh, Y. K. Tam, B. L. Mui, S. Omo-Lamai, M. E. Zamora, T. Shuvaeva, E. Arguiri, C. A. Thaiss, , O. A. Marcos-Contreras

This paper develops VCAM-targeted lipid nanoparticles to enhance drug delivery to the blood-brain barrier in acute ischemic stroke, reducing infarct volume and mortality.

bioRxiv · Jun 12, 2023Pharmacology & Toxicology

Supramolecular Organization Predicts Protein Nanoparticle Delivery to Neutrophils for Acute Lung Inflammation Diagnosis and Treatment

J. W. Myerson, P. N. Patel, N. Habibi, L. R. Walsh, Y.-W. Lee, D. C. Luther, L. T. Ferguson, M. H. Zaleski, M. E. Zamora, O. A. Marcos-Contreras, P. M. Glassman, I. Johnston, E. D. Hood, T. Shuvaeva, J. V. Gregory, , J. S. Brenner

This paper identifies nanoparticle supramolecular organization as a predictor of neutrophil uptake in inflamed lungs, demonstrating diagnostic and therapeutic potential for acute lung inflammation.

bioRxiv · Apr 15, 2020 · PreprintBioengineering