Author

E.-o. Essien

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

J. S. Brenner· 2 shared J. W. Myerson· 2 shared J. Wu· 2 shared L. S. Chase· 2 shared M. E. Zamora· 2 shared M. N. Patel· 2 shared O. A. Marcos-Contreras· 2 shared S. Omo-Lamai· 2 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

J. S. Brenner

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Author profile →

2 papers

Recent·Most cited

Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape without Side Effects

S. Omo-Lamai, Y. Wang, M. N. Patel, E.-o. Essien, M. Shen, A. Majumder, C. Espy, J. Wu, B. Channer, M. P. Tobin, S. Murali, T. E. Papp, R. Maheshwari, L. Wang, L. S. Chase, , J. S. Brenner

This paper identifies that lipid nanoparticle-induced inflammation arises from endosomal membrane damage and proposes strategies to mitigate it through galectin inhibition or ESCRT-recruiting lipids.

bioRxiv · Apr 16, 2024 · PreprintBioengineering

Physicochemical Targeting of Lipid Nanoparticles to the Lungs Induces Clotting: Mechanisms and Solutions

S. Omo-Lamai, M. E. Zamora, M. N. Patel, J. Wu, J. Nong, Z. Wang, A. Peshkova, L. S. Chase, E.-O. Essien, V. Muzykantov, O. A. Marcos-Contreras, J. W. Myerson, J. S. Brenner

This study identifies thrombosis as a risk of lung-targeted cationic lipid nanoparticles and proposes solutions to mitigate clotting without compromising targeting.

bioRxiv · Jul 21, 2023Bioengineering