A. Schaeffer

Global genomics of the man-o'-war (Physalia) reveals biodiversity at the ocean surface

The paper sequences 133 Physalia genomes and analyzes citizen-science images to reveal five distinct lineages and four species, with geographic population structure and long-distance dispersal.

Centrosome positioning independently of microtubule-based forces

The paper shows centrosome positioning is driven by actomyosin contractile networks and cell shape remodeling, not microtubule-based forces.

The cell cycle variant in multiciliated cells incorporates 2 centriole biogenesis cycles

This study shows the MCC cell cycle variant accelerates centriole biogenesis by overlapping two cycles to produce multiple mature centrioles without cell division.

Microtubules under mechanical pressure can breach dense actin networks

The paper shows microtubules can breach dense actin networks under mechanical pressure when immobilized.

Evaluating microbial contaminations of alternative heating oils

This study evaluates microbial contamination risks of alternative heating oils using CO2 monitoring and simulation, finding that some fuels resist contamination while others promote microbial growth.

Microtubules self-repair in living cells

This study demonstrates that microtubules self-repair in living cells by incorporating injected tubulin dimers, showing spatial and temporal dynamics in PtK2 cells.

Compensatory CSF2-driven macrophage activation promotes adaptive resistance to CSF1R inhibition in breast-to-brain metastasis

The paper shows that blocking CSF1R in brain metastases initially reduces tumor growth but is ineffective in established tumors due to compensatory macrophage activation, which is overcome by combining CSF1R and STAT5 inhibition.

Hematopoietic progenitors polarize in contact with bone marrow stromal cells by engaging CXCR4 receptors.

This study shows that hematopoietic progenitors polarize when in contact with bone marrow stromal cells via CXCR4 receptors, leading to cytoskeletal reorganization and centrosome-microtubule network polarization.