Author

M. Fragiadaki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

J. Serbanovic-Canic· 3 shared B. Tardajos Ayllon· 2 shared C. Souilhol· 2 shared D. Pirri· 2 shared E. Chambers· 2 shared H. Roddie· 2 shared L. Canham· 2 shared P. Evans· 2 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersPhysiology

J. Serbanovic-Canic

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

EPAS1 Attenuates Atherosclerosis Initiation at Disturbed Flow Sites through Endothelial Fatty Acid Uptake

D. Pirri, S. Tian, B. Tardajos Ayllon, S. Irving, F. Donati, S. Allen, T. Mammoto, G. Vilahur, C. L. Miller, T. Schenkel, E. Chambers, M. J. Dunning, J. Serbanovic-Canic, F. Botre, A. Mammoto, , P. C. Evans

This study shows EPAS1 reduces atherosclerosis at disturbed flow sites by promoting endothelial fatty acid uptake and metabolism, which is suppressed in obesity through triglyceride-PHD3 pathway.

bioRxiv · Dec 5, 2023Physiology

JAG1-NOTCH4 MECHANOSENSING DRIVES ATHEROSCLEROSIS

C. Souilhol, X. Li, L. Canham, H. Roddie, D. Pirri, B. Tardajos Ayllon, E. Chambers, M. Dunning, M. Ariaans, J. Li, Y. Fang, M. FRAGIADAKI, V. Ridger, J. Serbanovic-Canic, S. De Val, , P. Evans

This study shows JAG1-NOTCH4 signaling promotes atherosclerosis by repressing endothelial repair in response to low oscillatory shear stress.

bioRxiv · May 15, 2020Pathology

β1 integrin is a sensor of blood flow direction

I. Xanthis, C. Souilhol, J. Serbanovic-Canic, H. Roddie, A. Kalli, M. Fragiadaki, R. Wong, D. Shah, J. Askari, L. Canham, N. Akhtar, S. Feng, V. Ridger, J. Waltho, E. Pinteaux, , P. Evans

This study identifies β1 integrin as a sensor for blood flow direction in endothelial cells, showing it is activated by unidirectional but not bidirectional shear stress.

bioRxiv · Jan 3, 2019Cell Biology

A genome-wide RNAi screen identifies MASK as a positive regulator of cytokine receptor stability

K. H. Fisher, M. Fragiadaki, D. Pugazhendhi, N. Bausek, S. Brown, M. P. Zeidler

This study identifies MASK as a positive regulator of cytokine receptor stability through a genome-wide RNAi screen in Drosophila and validates its function in human cells.

bioRxiv · Sep 11, 2017Cell Biology