Author

M. G. Holbrook

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4

Frequent Co-Authors

J. R. Port· 4 shared C. K. Yinda· 3 shared V. A. Avanzato· 3 shared C. I. Shaia· 2 shared C. Martens· 2 shared C. Shaia· 2 shared J. C. Riopelle· 2 shared J. E. Schulz· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersMicrobiology

J. R. Port

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Host and viral determinants of airborne transmission of SARS-CoV-2 in the Syrian hamster

J. R. Port, D. H. Morris, J. C. Riopelle, C. K. Yinda, V. A. Avanzato, M. G. Holbrook, T. Bushmaker, J. E. Schulz, T. A. Saturday, K. Barbian, C. A. Russel, R. Perry-Gottschalk, C. I. Shaia, C. Martens, J. O. Lloyd-Smith, , V. J. Munster

This study investigates how SARS-CoV-2 infection affects airborne transmission in Syrian hamsters, finding that viral shedding and transmission efficiency vary by host and virus factors.

bioRxiv · Aug 15, 2022Microbiology

Infection- or vaccine mediated immunity reduces SARS-CoV-2 transmission, but increases competitiveness of Omicron in hamsters

J. R. Port, C. K. Yinda, J. C. Riopelle, Z. A. Weishampel, T. A. Saturday, V. A. Avanzato, J. E. Schukz, M. G. Holbrook, K. Barbian, R. Perry-Gottschalk, E. Haddock, C. Martens, C. I. Shaia, T. Lambe, S. C. Gilbert, , V. J. Munster

This study shows that vaccination and prior infection reduce SARS-CoV-2 transmission but increase Omicron competitiveness in hamsters compared to Delta.

bioRxiv · Jul 29, 2022 · PreprintMicrobiology

Western diet increases COVID-19 disease severity in the Syrian hamster

J. R. Port, D. R. Adney, B. Schwarz, J. Schulz, D. E. Sturdevant, B. J. Smith, V. Avanzato, M. G. Holbrook, J. Purushotham, K. A. Stromberg, I. Leighton, C. Bosio, C. Shaia, V. Munster

This study shows that a Western diet worsens COVID-19 outcomes in Syrian hamsters by increasing weight loss, lung damage, and systemic inflammation.

bioRxiv · Jun 17, 2021 · PreprintMicrobiology

K18-hACE2 mice develop respiratory disease resembling severe COVID-19

C. K. Yinda, J. R. Port, T. J. Bushmaker, I. Offei Owusu, V. A. Avanzato, R. J. Fischer, J. E. Schulz, M. G. Holbrook, M. J. Hebner, R. Rosenke, T. Thomas, A. Marzi, S. M. Best, E. de Wit, C. Shaia, , V. Munster

This paper shows that K18-hACE2 mice develop severe respiratory disease upon SARS-CoV-2 infection, resembling human severe COVID-19 with lung pathology and systemic inflammation.

bioRxiv · Aug 11, 2020Microbiology