Author

M. Georgiou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. Collin· 2 shared L. Armstrong· 2 shared M. Lako· 2 shared A. Buskin· 1 shared A. D. Rusu· 1 shared A. Kalitzeos· 1 shared A. Leung· 1 shared A. Lourdusamy· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCell Biology

J. Collin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Conjunctival epithelial cells resist productive SARS-CoV-2 infection

M. Lako, R. M. Jackson, C. F. Hatton, J. S. Spegarova, M. Georgiou, J. Collin, E. Stephenson, B. Vernon, I. J. Haq, R. Hussain, J. M. Coxhead, H. S. Mudhar, B. Wagner, M. Hasoon, T. Davie, , C. J. Duncan

The paper investigates whether conjunctival epithelial cells can be infected by SARS-CoV-2 and finds that while genome expression occurs, productive infection does not.

bioRxiv · Dec 20, 2021Cell Biology

Translational readthrough as a potential therapeutic for AIPL1-associated Leber Congenital Amaurosis in a patient-derived iPSC-retinal organoid model

A. Leung, A. Sacristan-Reviriego, P. Perdigao, H. Sai, M. Georgiou, A. Kalitzeos, A.-J. F. Carr, P. J. Coffey, M. Michaelides, J. Bainbridge, M. E. Cheetham, J. van der Spuy

This study uses patient-derived iPSC-retinal organoids to investigate translational readthrough as a therapy for LCA4 caused by AIPL1 mutations.

bioRxiv · Dec 17, 2021 · PreprintCell Biology

Progressive protein aggregation in PRPF31 patient retinal pigment epithelium cells: the mechanism and its reversal through activation of autophagy

M. Georgiou, C. Yang, R. Atkinson, K.-T. Pan, A. Buskin, M. Moya Molina, J. Collin, J. Al-Aama, F. Goertler, S. E. J. Ludwig, T. Davey, R. Luhrmann, S. Nagaraja-Grellscheid, C. Johnson, R. Ali, , M. Lako

This study shows that PRPF31 mutations cause progressive protein aggregation in RPE cells, which can be reversed by autophagy activation.

bioRxiv · Oct 11, 2021 · PreprintCell Biology

CG7379/ING1 suppress cancer cell invasion by maintaining cell-cell junction integrity

A. D. Rusu, Z. E. Cornhill, B. Canales Coutino, M. Castellanos Uribe, A. Lourdusamy, Z. Markus, S. T. May, R. Rahman, M. Georgiou

This study identifies CG7379/ING1 as a suppressor of cancer cell invasion by maintaining cell-cell junction integrity in Drosophila and human cells.

bioRxiv · Aug 20, 2020Cancer Biology