R. Ali

Indigenous probiotics Lactobacillus reuteri and Enterococcus faecium exhibit positive growth performance and disease prevention against extended-spectrum cephalosporin and fluoroquinolones resistant Salmonella enterica in broiler chicks.

This study shows that indigenous probiotics Lactobacillus reuteri and Enterococcus faecium improve growth and reduce Salmonella infection in broiler chicks compared to commercial probiotics.

The role of structural vs cellular remodeling in arrhythmogenesis: personalized computer models of atrial fibrillation.

This study uses personalized computer models to analyze how structural and cellular changes contribute to atrial fibrillation, showing that electrophysiological remodeling influences arrhythmogenic substrate and driver locations.

Progressive protein aggregation in PRPF31 patient retinal pigment epithelium cells: the mechanism and its reversal through activation of autophagy

This study shows that PRPF31 mutations cause progressive protein aggregation in RPE cells, which can be reversed by autophagy activation.

Spatiotemporal Control of Actomyosin Contractility by MRCKβ Signaling Drives Phagocytosis

This study identifies MRCKβ signaling as a key regulator of actomyosin contractility during phagocytosis, showing its role in membrane deformation and particle internalization.

Large-scale Genetic Characterization of a Model Sulfate Reducing Bacterium

This study characterizes the genetic essentiality and conditional phenotypes of Desulfovibrio vulgaris Hildenborough using a transposon mutant library under various metabolic and stress conditions.

An endophytic bacteria (Pseudomonas aeruginosa) strain translocated and protected tomato (Solanum lycopersicum L.) plants from its parasitic weed Phelipanche aegyptiaca

The paper investigates an endophytic Pseudomonas aeruginosa strain that moves between tomato plants and its parasitic weed Phelipanche aegyptiaca, enhancing biofilm formation and being detected in both xylem and weed tissues.

Topoisomerase II inhibitors induce cGAS-STING dependent inflammation resulting in cytokine induction and immune checkpoint activation

This study shows topo-II inhibitors like doxorubicin induce cGAS-STING dependent inflammation, cytokine production, and immune checkpoint activation in cancer cells, enhancing potential for immune checkpoint blockade therapy.

Biased signaling downstream of epidermal growth factor receptor regulates proliferative versus apoptotic response to ligand

This paper shows that in metastatic breast cancer, EGFR signaling is biased toward STAT1, leading to apoptosis, and that pharmacological biasing can enhance this effect.

HLA-B*39:06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression

This paper develops a mouse model expressing HLA-B*39:06 without murine class I MHC and shows it leads to T1D with reduced thymic insulin expression, despite normal T cell development.