Author

M. Guenther

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1 Organism:Xenopus· 1

Frequent Co-Authors

T. Hoefer· 2 shared A. Hirth· 1 shared A. Svorinic· 1 shared C. Fleck· 1 shared C. Niehrs· 1 shared C.-M. Cruciat· 1 shared D. F. B. Haeufle· 1 shared D. Papageorgiou· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

T. Hoefer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

DEAD-box RNA Helicases Act as Nucleotide Exchange Factors for Casein Kinase 2

E. Fatti, A. Hirth, A. Svorinic, M. Guenther, C.-M. Cruciat, G. Stier, S. P. Acebron, D. Papageorgiou, I. Sinning, J. Krijgsveld, T. Hoefer, C. Niehrs

The paper shows DDX proteins act as nucleotide exchange factors for CK22, enhancing kinase activity and revealing a new regulatory mechanism for protein kinases.

bioRxiv · Dec 20, 2021Biochemistry

Rules of nature's Formula Run: Muscle mechanics during late stance is the key to explaining maximum running speed

M. Guenther, R. Rockenfeller, T. Weihmann, D. F. B. Haeufle, T. Goetz, S. Schmitt

This paper proposes a biomechanical model to explain the allometry of maximum legged running speed, identifying muscle inertia as a key factor limiting speed in large animals.

bioRxiv · Oct 29, 2020Zoology

Optogenetic control shows that kinetic proofreading regulates the activity of the T cell receptor

O. S. Yousefi, M. Guenther, M. Hoerner, J. Chalupsky, M. Wess, S. M. Brandl, R. W. Smith, C. Fleck, T. Kunkel, M. D. Zurbriggen, T. Hoefer, W. Weber, W. W. A. Schamel

The study shows that the half-life of the ligand-T cell receptor complex determines T cell activation, supporting the kinetic proofreading model.

bioRxiv · Oct 1, 2018Immunology