Author

M. Hein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1

Frequent Co-Authors

J. Behrends· 2 shared A. Boisson· 1 shared A. Gross· 1 shared A. Hoelscher· 1 shared A. Kispert· 1 shared B. E. Schneider· 1 shared B. Kalsdorf· 1 shared C. Bouchart· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

J. Behrends

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Favorable histo-molecular remodeling of pancreatic ductal adenocarcinoma after Total Neoadjuvant Therapy including Stereotactic Body Radiotherapy

C. Bouchart, O. A. Senar, J. Navez, L. Verset, A. Boisson, M. Hein, K. Stosic, E. Quertinmont, V. Tafciu, S. Zhao, L. Mas, N. D'Haene, D. Van Gestel, L. Moretti, I. Rooman, , J.-L. Van Laethem

This study shows that combining FOLFIRINOX with stereotactic body radiotherapy remodels pancreatic ductal adenocarcinoma, improving stromal and metabolic features and prognosis.

bioRxiv · Apr 30, 2024 · PreprintCancer Biology

Sex differences in vaccine induced immunity and protection against Mycobacterium tuberculosis

G. H. Parvathy, D. Bhandiwad, L. Eggers, L. von Borstel, J. Behrends, M. Hein, D. Hertz, J. Marschner, Z. Orinska, S. H. E. Kaufmann, M. A. Flores-Valdez, H. Lotter, B. E. Schneider

This study investigates sex differences in immune response to TB vaccines in mice, finding that male mice show poorer BCG vaccine efficacy and specific CD8 T cell deficiencies compared to females.

bioRxiv · Apr 20, 2024Immunology

WNT6-ACC2-induced accumulation of triacylglycerol rich lipid droplets is exploited by Mycobacterium tuberculosis

J. Brandenburg, S. Marwitz, S. C. Tazoll, F. Waldow, B. Kalsdorf, T. Vierbuchen, T. Scholzen, A. Gross, S. Goldenbaum, A. Hoelscher, M. Hein, L. Linnemann, M. Reimann, A. Kispert, M. Leitges, , N. Reiling

This study shows that the WNT6-ACC2 pathway promotes lipid droplet accumulation in macrophages, which Mycobacterium tuberculosis exploits for growth, and that inhibiting this pathway enhances anti-tuberculosis treatment.

bioRxiv · Jun 26, 2020 · PreprintImmunology