M. Hernandez-Garcia

Within-patient evolution of plasmid-mediated antimicrobial resistance

This study tracks the evolution of plasmid-mediated antimicrobial resistance in hospitalized patients, revealing trade-offs between resistance levels and bacterial fitness.

Automatic discrimination of species within the Enterobacter cloacae complex using MALDI-TOF Mass Spectrometry and supervised algorithms

This paper develops machine learning models using MALDI-TOF MS data to accurately differentiate species within the Enterobacter cloacae complex.

Automatic antibiotic resistance prediction in Klebsiella pneumoniae based on MALDI-TOF mass spectra

This paper introduces a Bayesian model to predict antibiotic resistance in Klebsiella pneumoniae using MALDI-TOF mass spectra, outperforming existing methods by avoiding preprocessing and hyperparameter tuning.

The distribution of plasmid fitness effects explains plasmid persistence in bacterial communities

The study determines the distribution of fitness effects for plasmid pOXA-48 in gut bacteria, showing quasi-neutral effects and beneficial effects in some isolates, and links plasmid persistence to bacterial diversity and phylogeny.

Dissemination routes of the carbapenem resistance plasmid pOXA-48 in a hospital setting

This study characterizes the dissemination routes of the carbapenem resistance plasmid pOXA-48 in a hospital setting using mechanistic models and genomic data.