Author

M. Hyland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. G. Kay· 2 shared N. R. Forsyth· 2 shared O. Kehoe· 2 shared R. Morgan· 2 shared A. Piccinini· 1 shared A. Pisconti· 1 shared A. Stefan· 1 shared F. K. Jones· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

A. G. Kay

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2 papers

Recent·Most cited

THERAPEUTIC EFFECTS OF HYPOXIC AND PRO-INFLAMMATORY PRIMING OF MESENCHYMAL STEM CELL-DERIVED EXTRACELLULAR VESICLES IN INFLAMMATORY ARTHRITIS

A. G. Kay, K. Treadwell, P. Roach, R. Morgan, R. Lodge, M. Hyland, A. Piccinini, N. R. Forsyth, O. Kehoe

This study evaluates the therapeutic effects of hypoxically and pro-inflammatory primed MSC-derived EVs in inflammatory arthritis, finding normoxic EVs most effective in reducing joint swelling and improving histopathology.

bioRxiv · Jun 28, 2021Immunology

MSCs from syndecan-3 null mice exhibit enhanced adhesion to collagen type I, hyperactivation of the AKT pathway and increased efficacy in inflammatory arthritis

F. K. Jones, A. Stefan, A. G. Kay, M. Hyland, R. Morgan, N. R. Forsyth, A. Pisconti, O. Kehoe

This study shows that SDC3-deficient MSCs adhere better to collagen I, have hyperactive AKT signaling, and are more effective in treating inflammatory arthritis.

bioRxiv · Jun 12, 2020Immunology