Author

M. J. Freeman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

B. S. Klein· 1 shared C. L. Ober· 1 shared C. Siletti· 1 shared C. Strickland· 1 shared C. W. McIntire· 1 shared D. Amador-Noguez· 1 shared D. D. Shooltz· 1 shared D. J. Jackson· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperImmunology

B. S. Klein

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

C-di-AMP accumulation disrupts glutathione metabolism and inhibits virulence program expression in Listeria monocytogenes

C. Siletti, M. J. Freeman, Z. Tu, D. M. Stevenson, D. Amador-Noguez, J.-D. Sauer, T. N. Huynh

This study shows that c-di-AMP accumulation in Listeria monocytogenes disrupts glutathione metabolism, leading to reduced virulence gene expression and attenuated pathogenesis.

bioRxiv · Jan 18, 2024 · PreprintMicrobiology

Dissolved oxygen dynamics reveal biogeochemical tipping points driven by river corridor hydrology

M. H. Kaufman, R. N. Ghosh, J. Grate, D. D. Shooltz, M. J. Freeman, T. M. Ball, R. Loloee, C. W. McIntire, J. Wells, C. Strickland, V. Vermeul, K. A. Rod, R. D. Mackley, X. Lin, H. Ren, J. C. Stegen

The paper measures dissolved oxygen dynamics in a hydropeaked river system to identify hydrobiogeochemical tipping points driven by rapid hydrologic changes.

bioRxiv · Jan 31, 2020 · PreprintBiochemistry

Club cell TRPV4 as a damage sensor driving lung allergic inflammation

D. L. Wiesner, R. M. Merkhofer, C. L. Ober, G. C. Kujoth, J. E. Gern, R. Brockman Schneider, M. D. Evans, D. J. Jackson, T. F. Warner, N. Jarjour, S. J. Esnault, M. B. Feldman, M. J. Freeman, H. Mou, J. Vyas, B. S. Klein

The paper identifies TRPV4 in club cells as a sensor for junction damage that drives lung allergic inflammation through calcium and calcineurin signaling.

bioRxiv · Sep 19, 2019Immunology